Not really. That's an immediate noise cancellation function, which only works (a) with headphones and (b) by recording the outside noise and adding its inverse to the sound being played.
i don't mean necessarily doing active NC. i was more curious about doing an initial tune with the car at idle or while driving on the road as a way to compensate for the average. is there any value in doing something like that? maybe even just to tune the EQ profile of the car.