[phaedrus441]

Just anecdotal data, but in both my roles as an academic hospitalist and community hospitalist in the US (inpatient internal medicine doc, ie the person that cares for people admitted with acetaminophen overdose if not sent directly to the ICU), I have only seen two cases of intentional acetaminophen overdose (both survived, amazingly) and have heard of an accidental overdose only once (my colleague admitted them; older man taking 8-9 grams/day for about a month because he thought he was doing the right thing by avoiding opiates for hip pain).

Compare that to the three alcoholic cirrhotics I am currently caring for (which is a fairly common number where I work), and I personally don’t think acetaminophen is a very big deal for most people.

Also, we (hospitalists in the US) certainly see far more bad outcomes from OTC NSAID use contributing to GI bleeds and heart trouble (I’d say I care for a couple/month on average).