Yeah, the lack of nested formatting in rST is crazy. For me it's annoying I can't just do a simple monospace formatted link in pure rST. Sphinx helps a bit with that depending on what you want to link, but it's not really controllable at the rST level like it is in other markup.
Makes me wonder, since there is evil mode and opinionated Emacs disributions like Spacemacs und Doom Emacs, whether there is a potential for an org-mode focussed and optimized Emacs distribution.
Ease of use should be one of the core goals, then.
Also, rST can’t even do bold italics.