[oceanplexian]

Speaking specifically to the Pfizer vaccine, it’s gone from 95% effective against preventing severe symptoms against the Alpha variant to 88% against Delta in less than 6 months of the vaccine being widely available to the public (With some even less optimistic peer-reviewed studies coming out of Israel, I’m just going by what the CDC is reporting). So under these circumstances, maybe it makes sense to wait a year or two before making claims about the long-term effectiveness of the vaccines. If they aren’t effective long-term some people might make different decisions about what vaccine they decide to take.

[alexpw]

The mRNA vaccines were developed to target the spike protein of the Alpha variant. We got lucky it works so well against Delta, or else they would have had to roll out a new vaccine.

Based on your wording, it sounds like you have the mistaken impression that the mRNA vaccines are expected to account for and target all future variants. A future variant may have a large enough mutation to the spike protein and render them 0% effective. But they can rollout a new vaccine very quickly with EUA. Sorry if I've misinterpreted.

I don't remember ever seeing #s promising long term effectiveness, but eventually later seeing a chart with projected effectiveness waning over time. What they should do is be careful to present variant specific numbers. There's too much generalizing, like I did as well, lumping Pfizer and Moderna together.

[Reason077]

My comment was in regard to vaccine safety/side effects, not long-term efficacy.

[cies]

If it is quite safe but ineffective I also dont want it.

[Reason077]

They are proven to be highly effective at preventing severe cases of Covid-19, including the delta variant.

What we don't know (yet) is whether that efficacy will still be as strong 2, 3, or 5 years down the track. But that, IMO, is not a good reason not to get the vaccine today. Trust me, you don't want Covid!

[cies]

I literally want it. I prefer the virus over the treatment if the chances are 99.9%+ that I survive it. I expect it to me more like 99.99%+.

I say so since the beginning (when there was no vaccine): let me get it so I can help in old folks homes.

But what I got was mandates/lockdowns and free mRNA treatments. Not taking the jab means lots of hassle. I see what govts are doing to us. I dont like that. So I resist.