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by lambdaba 1724 days ago
Moreso, I sincerely believe the fear exacerbated by the ridiculous measures and the social isolation especially of the vulnerable and sick (no visits etc.) caused a substantial proportion of the deaths. We are not isolated organisms.

Fear causes stress. Chronic fear causes chronic stress. Chronic stress causes chronic cortisol. Chronic cortisol causes immunosupression.

2 comments

Indeed. And to flesh out in more detail, we caused:

- lack of sleep/exercise (which destroys the body's immunoregulatory capacities, leading to either a sort of acute immunosenescence like you said wrt fear, or alternatively leading to an overreactive immune system that kills via cytokine storm)

- decline in social interaction

- more time spent inside (which apart from the other correlates, very obviously leads to less sunlight). sunlight => vitamin d + nitric oxide; vitamin d is critical for respiratory pathology specifically, as well as just general health, and nitric oxide is very important as an immunoregulatory compound and as a preventer of strokes

- the general environment of fear/stress/anxiety (again, going to screw up the immunoregulatory balance of the body)

At least where I am (UK, and in particular, Wales), it seems our healthcare system is in the process of failing. It was already doing badly, and our response to Covid has tipped it over the edge. That alone will cause a significant amount of suffering and death.