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by pen2l 1741 days ago
Congrats on the nature publication! And congrats on making the HN frontpage, I think this is one of the few times I've seen a paper (as opposed to a news article about a paper) on the frontpage.

What type of epoxy do you use? I imagine depositing the epoxy in micro-doses must take a steady hand.

Your approach is great for its simplicity. Can you comment on the biocompatibility of the cured resin? Good enough to culture cells in?

1 comments

We were using a UV curing epoxy from Amazon, but we stopped because it had biocompatibility issue. Now we just use whatever is cheapest at the hardware store. It isn't hard at all to make the connections because the tubes go straight into the device and then we just epoxy on the outside and that is good enough.

My main contribution was testing the biocompatibility of the resins actually. The original resin was developed by the engineering team and while it worked well, some of the ingredients were extremely cytotoxic (to the point where if someone got it on their skin it would leave a nasty chemical burn). The resin used in the paper was a newer formulation that is completely biocompatible. The last bit of the paper is a quick dose-response assay with live cells.