At one point I prototyped a wasm framework inspired by Solid[1]. The results were very promising—an implementation of js-framework-benchmark was 41KB (18KB gzipped), and perforrmance was close to vanillajs. The developer ergonomics were definitely lacking, though.
Benchmark results (look for "cope")[2][3]
I definitely think whatever happens over the next few years, VDOMs are on their way out.
