Seeing how the Afghanistan war ended I don't think so. The last time the USA properly won a war was when they nuked cities and civilians, whereas China and Russia never went this far. Now given that USA is definitely the more belligerent of the 3, it might happen again.
Sure, but if the US command had for some reason been psychopathic enough, Afghanistan could have been leveled into a barren desert. Wars of occupation are messy and often inherently unwinnable. But the US can absolutely "output harm" anywhere on earth.