[gizmondo]

I happened to read it already.

Are you willing to bet that the tweaked Moderna vaccine (the trials of it was announced, right?) shows worse efficacy than the original? Odds 51:49 in your favor, null hypothesis of the same efficacy is a tie. That's generous I think, if nobody knows.

If not - why not?

[Zpalmtree]

Are you arguing we should just assume the new changes are good and roll them out without testing?

[gizmondo]

Yes, without large scale randomized efficacy trials. That's what we do with the flu.