|
|
|
|
|
|
by jrochkind1
1744 days ago
|
|
|
> The trials for Comirnaty and the Moderna vaccine both showed >90% effectiveness against PCR positive infections I don't believe the official trials for Moderna and Pfizer measured PCR positive infections at all. (They involved thousands of people, it was a time when PCR test were difficult to obtain; they remain expensive at that scale). I have not heard of Comirnaty, not sure about that. There may have been pre-delta studies that showed PCR infection effectiveness (Cite?), I don't think they were the official trials. |
|
|
According to this article, all of the major vaccine trials studied PCR positivity, not deaths/hospitalizations. https://www.bmj.com/content/bmj/371/bmj.m4058.full.pdf
> The first question is whether the right endpoints are being studied. Contrary to prevailing assumptions (including those of a former Food and Drug Administration commissioner8), none of the vaccine trials are designed to detect a significant reduction in hospital admissions, admission to intensive care, or death.9 Rather than studying severe disease, these mega-trials all set a primary endpoint of symptomatic covid-19 of essentially any severity: a laboratory positive result plus mild symptoms such as cough and fever count as outcome events (table 1).