A company without investors is a bootstrapped small business. Investors without a company are venture capitalists. Without investors, a company never becomes a startup, never has front-page articles in newspapers and magazines, never gets invited onto cable news for interviews, never hires expensive talent, never buys sports cars for its executives, never spends millions of dollars on advertising, etc.
Without investors, Holmes never would have mattered. The investments are what enabled her to commit the fraud.
I don't see anything obviously incorrect about all that, but it's irrelevant to the fact (if I'm not mistaken) that the investors didn't get a business and hire a CEO to run it, they found a business with a CEO.