[ninetenfour]

Tablets are important, so native apps for tablets makes sense if you think this is the main device people will use. ProCreate, Autodesk Sketchbook, etc. live on the tablet and native makes sense for that experience.

But then do not target desktop. You should target tablets and the pen-based interface on them.

[borisdalstein]

I will also target iPads and Android tablets as native apps, yes. But most professional users use a powerful desktop computer with a Wacom Intuos or Cintiq. Some professional work requires hundreds of layers, and in the context of animation, you're not going to make the next Studio Ghibli animation on an iPad. You need your 64GBs or RAM.