Thanks for sharing, very interesting. Haven't read the paper yet, but it seems promising as it mentions Hawkins and Subotai, from Numenta, who have been arguing something along these lines for many years. It is available in biorxiv [1].
OK I am still parsing the pre-print, but their approach seems very interesting. And equally interesting would be to see what happens if you apply HTM [1] to the same inputs model, e.g.:
> We next applied our paradigm to a morphologically and electrically complex detailed biophysical compartmental model of a 3D reconstructed layer 5 cortical pyramidal cell (L5PC) from rat somatosensory cortex (Fig. 2A). The model is equipped with complex nonlinear membrane properties, a somatic spike generation mechanism and an excitable apical nexus capable of generating calcium spikes
> We next applied our paradigm to a morphologically and electrically complex detailed biophysical compartmental model of a 3D reconstructed layer 5 cortical pyramidal cell (L5PC) from rat somatosensory cortex (Fig. 2A). The model is equipped with complex nonlinear membrane properties, a somatic spike generation mechanism and an excitable apical nexus capable of generating calcium spikes
[1] https://github.com/htm-community/htm.core