To some degree yes, but mainstream US is still far more culturally uniform from state to state than Europe's countries are. In Europe most of countries are nation-based and as such encapsulate also all the possible differences in ethnicities, languages, culture, religion and history to a much higher degree. Imagine each race/denomination/ethical group in US having their own independent state with their own laws and ways of life, and you get something like Europe.
But there is still a common language in the us.
And national TV-networks with lots of viewers in both those states.
Neither of those are true for Europe.
I would argue that it is fair to say that the US is more homogeneous than Europe, especially if you are talking about the entire Europe, and not just the EU.