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by kitcar 1763 days ago
The phase 1 study mentioned in this article:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323835/

("Dr. Dedhar and colleagues previously identified a unique compound, known as SLC-0111—currently being evaluated in Phase 1 clinical trials—as a powerful inhibitor of the CAIX enzyme")

1 comments

> known as SLC-0111

https://scholar.google.com/scholar?q=%22SLC-0111%22

AND

"U-104 (SLC-0111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki values of 45.1 nM and 4.5 nM, respectively. U-104 shows a significant delay in tumor growth in mice model. "

For research use only. We do not sell to patients.

100 mg: EUR 292

https://www.medchemexpress.com/U-104.html