[thehappypm]

It's an interesting concept. When your body makes antibodies against an active infection, it targets more than just the spike protein. Against the vaccine, it targets the spike protein 100% because that's all it has. As variants come and go, you should expect that the spike protein will change -- but it can't change that much because changing too much will reduce its ability to infect cells -- so it's a good thing to have a wide variety of antibodies against. However, having antibodies against other parts of the virus is useful too, since those might be more conserved with variants, but also they could be conserved less -- we don't really know.