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by walterbell 1758 days ago
From a recent BBC article on immunity, https://www.bbc.com/news/health-58270098

> There is a whole different suite of antibodies (known as immunoglobulin As) in the nose and lungs, compared with those (immunoglobulin Gs) that we measure in the blood. The former is more important as a barrier to infection. Natural infection, because it is in the nose rather than a jab in the arm, may be a better route to those antibodies, and nasal vaccines are being investigated too.

Intramuscular (arm injection) vs intranasal (inhaled) vaccines: https://news.ycombinator.com/item?id=28165287

Nasal vaccine trials: https://news.ycombinator.com/item?id=28284504