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I press it as soon as I see a popup about cookies or login or sales or basically anything at all.

I press it when there's a paywall.

I press it when the site doesn't do dark-mode.

I press it when adverts become annoying.

There also exists an auto-reader-mode plugin that you can tell to always open that site in reader-mode in future.

Reader mode is great. Hope it doesn't become popular so website start trying to stop it working.