Everytime that comment is referenced, people forget that the rest of comments were mostly positive plus constructive criticism or challenges they'd face.
Yes, and BrandonM's comment was constructive criticism. He was trying to help Drew with his YC application (that's what "app" meant back then) and clearly wanted it to succeed ("I only hope that I was able to give you a sneak preview of some of the potential criticisms you may receive. Best of luck to you").
https://news.ycombinator.com/item?id=27068148
https://news.ycombinator.com/item?id=23229275