We touched upon this some time back. If you don't want to dig through the whole messy thread[1], I would recommend "Placebo-Controlled Trials of Covid-19 Vaccines — Why We Still Need Them"[2].
[1]: https://news.ycombinator.com/item?id=27987904
[2]: https://www.nejm.org/doi/full/10.1056/NEJMp2033538
We touched upon this some time back. If you don't want to dig through the whole messy thread[1], I would recommend "Placebo-Controlled Trials of Covid-19 Vaccines — Why We Still Need Them"[2].
[1]: https://news.ycombinator.com/item?id=27987904
[2]: https://www.nejm.org/doi/full/10.1056/NEJMp2033538