[phaedrus441]

Upside: there are very few indications for an MRI with contrast, and epidemiological studies have shown current gadolinium-based contrast appears to be well-tolerated (i.e. very low risk of nephrogenic systemic fibrosis in patients with renal failure). Downside: if an MRI protocol calls for contrast, then it’s necessary to use contrast to obtain the information desired (i.e. there’s often little use getting a non-contrasted MRI of the protocol calls for contrast but there is a contraindication).