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by u801e 1759 days ago
What study shows 80% or greater efficacy for primary immunity versus secondary immunity via vaccination? Do they go into detail regarding how long the immunity lasts, and whether it covers varients? Viruses that cause the flu or common cold change from season to season, so immunity (either primary or secondary) doesn't really protect against a subsequent varient.
1 comments

>What study shows 80% or greater efficacy for primary immunity versus secondary immunity via vaccination

The CDC claims being unvaccinated was associated with 2.34 times the odds of reinfection compared with being fully vaccinated. Most vaccines are 90+ effective. Say for example moderna is 95.3% effective, natural immunity would be 89% (100% - 4.7% x 2.34)

https://www.cdc.gov/mmwr/volumes/70/wr/mm7032e1.htm

>Do they go into detail regarding how long the immunity lasts, and whether it covers varients?

There is a lot of information missing on duration, but we know people who were infected with SARS-CoV-1 still have antibodies 20 years later. Natural infection triggers an immune response on many more parts of the virus than the vaccine, so protection against variants should also be good or better than the original vaccine, but not better than a booster vaccine tailored specifically to a given variant.