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by walterbell
1763 days ago
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If one _must_ take a vaccine to satisfy a legal mandate, one would prefer a vaccine that provides sterilizing immunity, i.e. a permanent solution, rather than years of variant-specific booster shots with temporary, non-sterilizing immunity. From a recent publication by UK SAGE, https://www.gov.uk/government/publications/long-term-evoluti... > Whilst we feel that current vaccines are excellent for reducing the risk of hospital admission and disease, we propose that research be focused on vaccines that also induce high and durable levels of mucosal immunity in order to reduce infection of and transmission from vaccinated individuals. This could also reduce the possibility of variant selection in vaccinated individuals. A short article on nasal vaccines, https://www.statnews.com/2021/08/10/covid-intranasal-vaccine... > Vaccines that are injected into the arm have done a spectacular job at preventing severe disease and death. But they do not generate the kind of protection in the nasal passages that would be needed to block all infection. That’s called “sterilizing immunity.” The fact that the vaccines don’t block all infections and don’t prevent vaccinated people from transmitting isn’t a big surprise, said Kathryn Edwards, a vaccine expert at Vanderbilt School of Medicine. The MMR vaccine is sterilizing, there are no booster subscription plans required. It is unfortunate that hundreds of millions of people now have category confusion where they mistakenly equate rushed, temporary, tactical vaccines (focused on symptom and mortality reduction) with proven vaccines (like MMR) that provide long-term immunity and have many years of safety data. |
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https://www.mayoclinic.org/diseases-conditions/measles/exper....
Also, people do get tetanus boosters as needed and some people do have to get another round of Hep-B again. My wife who is about to enter a nursing program has to go through another regimen of Hep-B because her medical paperwork shows she doesnt have immunity. She was vaccinated. It does occur in some people that their body does not retain immunity.
Now yes, I would like to see a better COVID shot. Or atleast know the full limits of the COVID shot. We are still not 100% how long someone has immunity. Hopefully it is a long time. If it turns out to be short, well yes I think we all want longer. There is also no garuntee of protection against variants. Measles could very well morph out in the wild as something different and current MMR vaccines render useless. I would actually say it is not an if, but when. As it is common for things to evolve over time.