[LifeIsThermal]

Natural immunity gives "ultrapotent" antibodies that works for 23 variants, including delta. That´s what will end this pandemic. Everyone will get infected, vaccinated and unvaccinated.

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants

”Wang et al. identified four antibodies from early-outbreak convalescent donors that are potent against 23 variants, including variants of concern”

”The B cells isolated from donor-derived blood samples were sorted for antibody identification. This led to the identification of four potent neutralizing antibodies targeting the spike RBD. These antibodies showed a high affinity for the SARS-CoV-2 spike even at nanomolar concentrations.”

”The findings revealed that of 4 antibodies, two bound to RBDs in the “up position” and two bound to RBDs in the “down position.” Moreover, three out of four antibodies directly blocked the RBD – ACE2 interaction, and one indirectly inhibited the interaction through steric hindrance - the slowing of chemical reactions due to steric bulk.”

”By conducting multiple rounds of selection using combination treatments with two antibodies, it was observed that antibody combinations might reduce the risk of escape mutation acquisition and subsequent development of resistant viral variants.”

https://science.sciencemag.org/content/early/2021/06/30/scie...