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by elevaet 1775 days ago
One danger of chronic ketamine use is bladder damage.
3 comments

From what I've read about people using Ketamine for antidepression, they tend to use a very small dose at as long an interval as possible while still being effective, while the reports of bladder damage seem to be when people use large quantities (a few grams) per day for months. That is, if you're using it medically, rather than for recreation, its probably not a risk. Even recreationally, unless you're abusing it, its likely not a big risk.

I think a big part of the issue is that you quickly develop a tolerance to Ketamine, so if you're a daily user, there's a strong tendency to up the dosage to maintain its effect. If you're a casual user or are careful to spread it out to avoid tolerance buildup, I think it can be avoided.

With that said, you're absolutely right that it is a danger that needs to be kept in mind, but from what I've read, if you're not abusing it, the risk seems low.

You're right, taken in a medical context there would be no risk of this. Just wanted to put the bladder damage risk on the radar, so that people are aware that there are physical consequences to abuse. You know, a lot of people self-medicate and there's a fine line between self-medication, recreation, and abuse.
I totally agree with the perspective in that blog. I just wanted to mention one of the known dangers of chronic ketamine use in the spirit of harm-reduction, because I don't think the bladder damage risk is that well-known, and sometimes people become seduced by the charms of ketamine and end up taking the drug far more often than when they set out.
You have to take really large amounts daily to get bladder problems.