[jhbadger]

My issue with spreadsheets is that they don't encourage reproducible science. For example, if you write code in R or python to log transform your data, you can look at the code and see that it has been done. If you have a spreadsheet that you (or worse, someone else) has created, you can maybe look at the values and guess it has been log transformed, but you can't know for certain that was the case and no other transformations were applied.