[jesusjones]

Canadians and Mexicans can apply for a NAFTA Work Visa (TN) that is simpler to get. You can apply for 1 to 3 years and you only need a letter from the employer validating that you have been accepted to work in a US company.

[jamesteow]

You also need to have some documents proving that you are qualified for the role. This includes diplomas, license, university transcripts, and a resume with relevant work experience.

[null_ptr]

Are specific parts of the transcript such as GPA or individual course grades of any importance, or is the completion of a degree + relevant courses in your specific field enough?

[mallipeddi]

They generally ask for the full academic transcript (which has grades in it). Btw do not be worried if you don't have stellar grades/GPA - USCIS doesn't care about that. Your immigration lawyers just need to make a case that your education plus work exp (if any) is relevant to the job the company is hiring for.