[knuthsat]

Nice to see your focus on women's health. The amount of women with recurrent/embedded UTIs and other issues close to the vagina is enormous.

I was quite surprised to find out there are thousands of women suffering decade long issues with no help or just enormous, health devastating doses of antibiotics (multi-year long therapies).

There's been so many approaches over the years (I watched the d-mannose just explode in sales when previously there was none available) but they do not seem to work completely.

There are also small research groups trying to figure out what's happening but there's still no widely accepted therapies. For example, doctors from most EU contries would never prescribe the amount of antibiotics required for multi-year therapies.

It was also quite surprising to me, as a male, when I got my first UTI, they gave me quite a lot of antibiotics, but then when my wife complains about it, she gets silly advice (get pregnant, drink multivitamins, it's probably not UTI [until she starts having kidney infections or urinates blood]).

[ishishah]

Thanks! And I hear you, and recurrent & the secondary infections and the cyclic nature of it all are terrifying, to say the least, and the truth is also that in many cases, the recurrence is due to resistant bugs, that are just not eliminated by current care of Abx. Not to mention, some Abx when systemically administered, lead to major alterations in the gut microbiome as well. All in all, its not a good situation. I'm sorry to hear about your and your wife's infections, and hope we can contribute to reducing that burden somewhat for so many people.