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I can't download the paper. I'm sorry, but reading the abstract, I don't see how that paper supports your argument.

"Highlights

• Chronic Pb exposure could result in a lower weight gain in rats and a higher Pb content in the brain of model rats.

• Pb exposure reduced activities of key enzymes of glucose metabolism in the brain.

• Pb exposure could disrupt the insulin signaling pathway in the hippocampus of rats."

[Gauge_Irrahphe]

Lower insulin is good. Some of these proteins are targeted by Rapamycin.

The glucose transports are increased, (GLUT3 is the one that supplies axons) and the rats weighed less.