[new299]

> you would want to integrate a number of preparation steps with the sequencer

I think this is unlikely, Grail like everyone else probably just do standard sequencing runs with their own prep.

The issue is that Illumina make something like 10x on sequencing consumables.

So if Illumina were to sell a sequencing based test, they have large margins they can cut into to undercut anyone else.

That said, Illumina's dominance in sequencing is probably ending in ~2024 anyway (when basic patents expire).

Grail is not Illumina, it's a spinout that they want to acquire back in. Most likely this is because Illumina see that:

a) This Grail experiment is working out. b) They're going to lose their dominance in sequencing, and they want to acquire downstream applications.