I get annoyed with AV when it quarantines "Potentially unwanted software" like ProduKey. While it may be able to be used maliciously, that's not why I have it installed, and I do want it on my machine.
My win10 install recently started deleting my install of qBittorrent, which I very much want installed and use daily, as "potentially unwanted software". Exceptions kept getting ignored so just today I disabled the entire category of potentially unwanted software in win defender. It feels like they're just getting capricious in their scope for flagging things now.