[leephillips]

By a large-scale calculation I have in mind something like this: https://arxiv.org/pdf/2006.09368.pdf, which is in your field of astronomy. It uses about a billion dark-matter elements and was run on the Cobra supercomputer at Max Planck, which has about 137,000 CPU cores. It used the AREPO code, which is a C program that uses MPI. If you know of any calculation in this class using Python I would be interested to hear about it. But generally one doesn’t have one’s team write a proposal for time on a national supercomputing center and then, if it is approved, when your 100-hour slot is finally scheduled, upload a Python script to the cluster. But strange things happen.

EDIT: Yes, numba is impressive.