[hondo77]

You set out to ride 365 miles without chamois cream?

Ouchie.

[ska]

If your set up is good and you are used to regular riding shouldn't be a problem for 30 days of ~120 let alone 3. Assuming proper shorts and a good seat, of course.

[zikduruqe]

Brooks B17, plain street shorts, no chamois... it is like sitting in your favorite easy chair.

[matsemann]

For a short ride, perhaps. After a while most people will get chafing sores. A hard saddle, proper position and padded shorts "hurts" a bit on the sitting bones, but after one's adapted one can bike almost forever without any bum issues.