[golergka]

I wrote a big comment and deleted it, because it all depends on your notion of reasonable safety. If you look transgender, you will certainly get glances and some occasional verbal aggression, but as long as you follow the basic common sense safety rules, I doubt that you'll have to worry about something worse. Russia is a huge place, and living in a center of Moscow does feel like one of the most modern, shiny European cities. There's plenty of middle class (by US and Europe standards; they're at least upper-middle class by Russian standards) people living by progressive western values. But there's plenty of places that aren't that welcoming.