[AnIdiotOnTheNet]

Not really. Physics, biology, and nutrition science all agree pretty conclusively that eating fewer calories than you expend will lead to weight loss.

There are a large number of factors that go into some people seeming to be able to eat large numbers of calories while others can't despite similar expenditures that we're still figuring out, but if you want a 100% guaranteed way to lose weight it is this: track your calories and make sure you eat fewer than you expend. If you want to keep it off, don't eat more than you expend.

Source: lost >150lbs and kept it off until this pandemic fiasco where I put about 30 of it back on.

As noted by others, this is simple. It is not necessarily easy. We're still working on figuring out why some people find it easy and others don't. Gut microbiome science seems promising.