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by baq 1814 days ago
> Maybe you're in the wrong thread, then?

maybe. or maybe the thread is pointless and i'm just pointing it out.

> The scenario you are describing is the immunocompromised person whose body can't quite kill the virus, but also puts selection pressure on it. Such cases have been described, but whatever mutation would come out of that is not necessarily going to be much more effective at overcoming the defenses of a normal immune system.

i'd wager more than 99% of those mutations won't be more effective. i'm worried about the tail risk in the remaining 1%. i don't know how many mutations are needed for the virus to become sufficiently different for human immune system to stop being recognized and this scenario is the best way to find out.

> The Sars-CoV2 virus will almost certainly stick around and it will keep mutating, even with the best of vaccination efforts. Nature finds a way. We'll have to get used to it.

no disagreement about that. in the long run we're all dead anyway. my issue with just letting it run its course is timing and cost - the argument is that it gets much easier much quicker for all of us with the best vaccination effort compared to alternatives.