I think the core problem is that wine needs to be tweaked and adjusted for the applications which are running, and often running certain software requires strange things with winetricks. It’s not stable enough for a distro
Which is a subsystem of windows to run linux, not a subsystem consisting of windows to run on linux. Ie that doesn't solve the problem of "I don't want to run Windows but want Windows software", but rather it solves the opposite problem of "I'm on Windows and want to run Linux software".