[hoseja]

Probably that letting the slow-GMO survive in a natural environment for hundreds of years does wonders for ironing out the really bad bugs.

I'm not anti-GMO but i've been more wary ever since I realized it will inevitably be used to make better citizens (and not by making them better humans).

[petre]

It depends. There's a number of dog breeds with known genetical issues.

GE is a double edged sword just like nuclear energy. With great power comes great responsability.

[hoseja]

Those are mostly innovations of the latest century or so, bred "scientifically", regulated by dog breed foundations and chasing dog-show metrics.