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by Sainth 1830 days ago
This sounds somewhat similar to symptoms I am having. Currently on a 5 month journey trying to get a diagnosis.

I have abdominal pain, headaches, high blood pressure with periodical orthostatic hypertension (my blood pressure goes up in the standing position; it is supposed to go down), tremors, tachycardia, fatigue, difficulty concentrating, constipation or diarrhea, severe sleep disturbances, muscle spasm and cramps, hot flushes, cold hands and feet, and I have some episodes of euphoria, panic attacks and paranoia. Same as you I have some days where I feel just fine.

I have had the same experiences as you when it comes to doctors, they do a lot of tests, the tests come back inconclusive and then they just shrug. At least I have a nice GP that says that he has no clue what is wrong with me but that something is definitely wrong.

So far we have done a lot of blood work, various urine and stool samples, CT-scan and MRI of abdomen. The only thing they have been able to find so far is slightly elevated noradrenaline/norepinephrine levels (three times) and some cysts on my left kidney.

The elevated noradrenaline could be because of a pheochromocytoma (adrenaline producing tumor), but when I have done the 24-hour urine test for that it comes back negative.

The only thing that I have found to work is to eat a low tyramine diet which seems to greatly reduce the symptoms, though not completely remove them.

It might not be the same as you are having problems with, but I do see a lot of similarities.

My email is in my profile, let me know if you want to compare notes.

2 comments

Yes, definitely. I will email you after work today. I have also been evaluated for a pheo with negative results - the sudden panic attacks out of nowhere seem to trigger this diagnostic pathway.

I will try to reduce dietary tyrannies - that is a good idea.

And are you taking monoamine oxidase inhibitors?