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I don't want to diminish what people having PTSD have to endure, but physical changes in the brain don't mean much without quantification. Regular learning alone also leaves physical and lasting changes in the brain.

I mention this because pointing to the physicality of psychological conditions often induces a sense of fatalism that often isn't warranted per se, and can become some sort of self-fulfilling prophecy.

Again, this does not mean people should just pull themselves up. It does suggest that people could in principle learn coping mechanisms (through therapy etc.) to a degree that allows for leading a fulfilling life, even with PTSD manifesting physically in the brain.