[perl4ever]

I don't expect anything in particular. As I wrote, I've tried it and it doesn't do anything amazing. I had previously tried it on recommendation from a sleep specialist before I read about the idea that it reverses metabolic damage from sleep deprivation.

Over the counter supplements usually seem to have way too large a dose, and I've read they can be very inconsistent too.

The point is, I read this amazing study, and it may be somehow incorrect or even fraudulent, but it is what it is. Sleep deprivation kills. The claim is that via, not one, but any of several substances, that can be reversed, at least in lab insects/animals.

I definitely am not advising anyone take any supplements. I want to clearly state that I don't experience any particular beneficial effects from anything I've tried.

I just am saying that uncovering the reason why sleep is needed has to have world changing applications, or end up as a spectacular debunking, it seems to me.

[raducu]

I understand and I know certain people use mega-dosages(10-15 miligrams) to protect themselves from neurotoxicity of certain drugs, but I'm sure that's just bro-science.

I would steer away from melatonin as a supplement for anything other than sleep, because it is a powerful hormone and while the science is lacking, it's better not to mess with such a powerful and important hormone.

[perl4ever]

I really wish for reform in regulation, so that quality and dosage of over the counter supplements could be trusted. I haven't heard of any groundswell of support for that, though. People say that it's a problem with cannabis supplements too.