[detritus]

Actually, Spice proper used a fairly benign synthetic cannabinoid. It was only after the market showed promise and after they were banned that slew of cheaper knock-offs that became commonly known as 'Spice' (despite having different brand names) came onto the illicit market, using other synthetics that were cheaper/easier to produce, but far-less tested, and deployed and sold in higher strengths by people who were far more cynical.