[ericbarrett]

The issue seems to be with the DNA -> mRNA transcription required by the adenovirus vector of the J&J and AstraZeneca vaccines, leading to mutated spike proteins which can cause clots. The Pfizer/Moderna shots don't use this mechanism so weren't the subject of the paper.

(This is not my specialty at all, just summarizing the abstract & what other commenters wrote since nobody replied to you yet)

I'm sorry about your father-in-law.

[giantg2]

Oh, I see. So similar mutations don't occur with straight mRNA. I think that makes sense. But also I thought the exact spike protein structure could vary with mRNA vaccines too based on the patient's genetic make up because the mRNA only encodes a portion of the spike and the rest of the spike is generated by the host cell.

I don't know, that not my area either. My main two points are that if covid itself can increase risk of stroke and now some covid vaccines can too, then I wonder if other covid vaccines might have contributed to this anecdotal one. The second point plays into the first. I would be less likely to question it if we had better reporting in the VAERS system.

He actually seems fine now, so he recovered quickly.