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by rsa4046
1856 days ago
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“In the case of a translating ribosome, a frameshift can either result in nonsense (a premature stop codon) after the frameshift, or the creation of a completely new protein after the frameshift. In the case where a frameshift results in nonsense, the NMD (nonsense-mediated mRNA decay) pathway may destroy the mRNA transcript, so frameshifting would serve as a method of regulating the expression level of the associated gene.” Nonsense-mediated mRNA decay.
Love this term! :) |
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