@fdej: what successor to ctypes did you have in mind? Other than the names (I prefer i8 over c_int8, but easy to work around) and lack of ergonomic interop with python ints, are there other issues you're aware of?
My number one wish would be the ability to read definitions from .h files automatically. Other than that, I've had some issues with memory management with ctypes (objects being deallocated prematurely) that I never had with Cython, but that may just be my own fault. I agree about the lack of interop with Python ints.
> My number one wish would be the ability to read definitions from .h files automatically.
This was originally a feature of ctypes but was dropped before stdlib inclusion because it's difficult to solve in the general, "public distribution" case. Nonetheless I don't think there's any need to replace ctypes to reintroduce it, it was done as a library / external tool before and still could be.