[d0mine]

Mentioning Putin (a vilified figure) in the first sentence indicates that it is a preemptive strike to discredit the journal in anticipation of the publication of successful results of phase III of the trial.

There are obviously issues with peer review but the scientific method is the best we've got.

[bsder]

Everybody is the world is cheerleading for a non-mRNA vaccine that doesn't require negative stupid celsius to store, and the Russians still can't drive through that gigantic gap.

The Brazilian report went into quite solid detail about why they rejected the Gamaleya vaccine--read for yourself.

https://blogs.sciencemag.org/pipeline/archives/2021/04/28/br...

Original slides in Portugese: https://www.gov.br/anvisa/pt-br/assuntos/noticias-anvisa/202...

[webmobdev]

The Russian vaccine isn't the only non-mRNA vaccine - India's Covaxin and Oxford / Astrazenaca's Covishield (as it is marketed in India) also doesn't require the kind of cold-storage that the Pfizer or Moderna vaccines do. [1]

Interestingly, India's Covaxin also had a similar controversy as Sputnik-V and critics accused it of being hurried and rushed through without going through all the trials:

    Experts wondered how a vaccine was cleared for emergency use by millions of vulnerable people when its trials were still underway. The All India Drug Action Network at the time said that it was "baffled to understand the scientific logic" to approve "an incompletely studied vaccine". It said that there were "intense concerns arising from the absence of the efficacy data".

    Both the manufacturer and drug regulator had defended Covaxin, saying it was "safe and provides a robust immune response" ... Bharat Biotech had said that Indian clinical trial laws allowed "accelerated" authorisation for use of drugs ... It had promised to provide efficacy data for the vaccine by February, which it has now done. [2]

[1][2]: https://www.bbc.com/news/world-asia-india-55748124

[d0mine]

The issue from the sciencemag link (replication-competent” adenovirus in the vaccine) seems plausible though the makers call it a disinformation compaign https://sputnikvaccine.com/newsroom/pressreleases/the-gamale...

It looks like there is no actual evidence: "Anvisa even though initially said that it detected RCA, admitted that it did not undertake any tests of the vaccine and was referring to a regulatory limit in Russia on potential RCA presence."