[briandoll]

Every application and environment is different. The great thing about cloud providers is that they are so easy to get up and running. Test it out! Benchmark your app in both environments and compare how it performs. Weight the costs/benefits of both solutions (not just in terms of performance, but also in maintenance, friction to change, etc.) and go from there.

[bdheeman]

Don't forget to evaluate/review security and, or privacy of your data and applications in public cloud computing environment ...