[sparkling]

I use Fedora because i like to have the vanilla GNOME experience out of the box. I also like that i don't need to undo all the snap stuff like in current Ubuntu versions, just plain old boring packages (snap and flatpak are both optional).

But overall, they are really similar.

[gtirloni]

flatpak is great for apps like Telegram, Discord, Zoom, Teams, etc.

[IceWreck]

For telegram you can just use the package from rpmfusion. I do use flatpak for proprietary software like Discord, Zoom, etc.

[nix23]

AppArmor vs SELinux would be another one...

[stjo]

There are some internal differences which may matter to you if you develop software targeting RHEL or CentOS.