[Scandiravian]

So prions are simply a result of entropy? Am I understanding that correctly?

[lazide]

All evolutionary change (and life itself) is due a combination of differences of entropy (aka an energy gradient existing), combined with randomness in the current environment allowing mutation/change and hence selection pressure.

[Ericson2314]

I would say life is an artifact of non-erodicity. Rare things that self-replicate are over-abundant in hindsight.