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by jwq1 1894 days ago
Have there been any follow-up studies done on humans?
1 comments

The author shared the following insight.

"[It's] nearly impossible to study using non-invasive measures in humans. However, there is a paper on effects of exercise in humans where the authors talk about an in vivo correlate of adult neurogenesis:

Pereira AC, Huddleston DE, Brickman AM, Sosunov AA, Hen R, McKhann GM, Sloan R, Gage FH, Brown TR & Small SA (2007). Proc Natl Acad Sci USA 104, 5638–5643.

This is pretty old, so maybe there would be more recent studies to be found. However, thinking about the relevance of using rodents to study human brain (because we are of course interested in the human brain, not the rat brain), there is close resemblance in terms of structure and function. Please see the following papers for details: Clark RE, Squire LR. 2013. Proc Natl Acad Sci U S A. 110 Suppl 2(Suppl 2):10365-70 Bergmann E, Zur G, Bershadsky G, Kahn I. 2016. Cereb Cortex. 26(12):4497-4512."

- Miriam Nokia